Clinical features of infectious spondylitis in patients with COVID-19
https://doi.org/10.14531/ss2023.1.85-92
Abstract
Objective. To analyze the clinical features of the course of infectious spondylitis in patients with COVID-19.
Material and Methods. A continuous retrospective study was performed with the analysis of medical records of 52 patients with infectious spondylitis who were treated in 2021–2022. The patients were divided into two groups: the study group (n = 24) – with a history of a new coronavirus infection; and the control group (n = 28) – without coronavirus infection.
Results. The features of infectious spondylitis in patients with COVID-19 are the predominance of facultative anaerobic gram-negative flora in the focus of infection, a higher frequency of multilevel lesions, a tendency to increase the number of negative results of surgical treatment, and a chronic protracted course. At the same time, the course of infectious spondylitis associated with COVID-19 is accompanied by less destructive changes in the affected segment leading to a violation of the supporting function of the spine. Nevertheless, there is a statistically significant increase in the period of relief of the inflammatory process in the spine in these patients: 18.04 ± 3.84 weeks in the study group and 10.08 ± 2.34 weeks in the control group (Uemp < 240; p = 0.001).
Conclusion. The secondary infectious lesion of the spine against the background of a new coronavirus infection is caused by gram-negative pathogens in the vast majority of cases, proceeds without severe bone destruction, with a tendency to a chronic protracted course. Surgical treatment of COVID-associated spondylitis is associated with a higher risk of postoperative complications.
About the Authors
I. V. Yesin
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
4, build 2, Dostoyevskogo str., Moscow, 127473, Russia
Russian Federation
Russian Federation
senior researcher, Scientific Department of Osteoarticular Disease
E. O. Perecmanas
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
4, build. 2, Dostoyevskogo str., Moscow, 127473, Russia
Russian Federation
Russian Federation
Head of Scientific Department of Osteoarticular Disease
T. E. Tulkova
National Medical Research Center of Phthisiopulmonology and Infectious Diseases
4, build. 2, Dostoyevskogo str., Moscow, 127473, Russia
Russian Federation
Russian Federation
DMSc, Head of Research Coordination Department
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Review
For citations:
Yesin I.V., Perecmanas E.O., Tulkova T.E. Clinical features of infectious spondylitis in patients with COVID-19. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2023;20(1):85-92. https://doi.org/10.14531/ss2023.1.85-92
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