POSSIBILITY OF SPONTANEOUS BIOELECTRIC ACTIVITY RECORDING IN THE SPINAL CORD INJURY
https://doi.org/10.14531/ss2008.4.58-64
Abstract
Objective. To assess diagnostic possibilities of registration of spontaneous bioelectric activity of the spinal cord from the skin surface and to study variability of the spinal cord functional state at different stages of spinal injury. Material and Methods. Results of dynamical examination of 12 patients with spinal cord injury (SCI) at acute and intermediate stages were analyzed. A functional state of the spinal cord was assessed by simultaneous recording of electrospinogram (ESG) and direct current potential (DCP) from the skin surface in accordance with unipolar technique using 6-channel DC amplifier. Results. In all patients with acute SCI negative DC shifts (18.73 ± 2.47 mV) were registered in the injury region with respect to cephalad recording channels. In caudad channels a DC potential was more positive, on average by 4.26 ± 0.53 mV. Changes in slow electrical activity of the spinal cord were less specific and reflected its current functional state. In patients with acute SCI a decrease in ESG amplitude by 30–50 % was recorded in all recording channels. In patients with intermediate- stage of SCI statistically significant increase in ESG amplitude was recorded in the region of injury and caudad recording channels. Conclusion. Procedure of simultaneous DC and ESG recording provides identification of the level of electrophysiological disturbances and estimation of function changes in the injured and adjacent regions of the spinal cord which is necessary for the assessment of disease course and therapy efficacy.
About the Authors
Albert Akramovich Sufianov
East-Siberian Minimally Invasive Neurosurgical Centre, Military Hospital No.325, Irkutsk
Russian Federation
Russian Federation
Andrey Grigoryevich Shapkin
East-Siberian Minimally Invasive Neurosurgical Centre, Military Hospital No.325, Irkutsk
Russian Federation
Russian Federation
Galina Zinovyevna Sufianova
East-Siberian Minimally Invasive Neurosurgical Centre, Military Hospital No.325, Irkutsk
Russian Federation
Russian Federation
Yury Grigoryevich Shapkin
East-Siberian Minimally Invasive Neurosurgical Centre, Military Hospital No.325, Irkutsk
Russian Federation
Russian Federation
Mikhail Vitalyevich Taborov
East-Siberian Minimally Invasive Neurosurgical Centre, Military Hospital No.325, Irkutsk
Russian Federation
Russian Federation
References
1. Аладжалова Н.А. Медленные электрические процессы в головном мозге. М., 1962.
2. Костюк П.Г. Электрофизиология спинного мозга // Современные проблемы электрофизиологических исследований нервной системы. М., 1964. С. 115–131.
3. Оноприенко А.П. Клинико-диагностическое значение показателей биоэлектрической активности спинного мозга по данным электромиелографии // Врачебное дело. 1984. № 1. С. 105–106.
4. Сорохтин Г.Н., Темпер Ю.Б. К вопросу о природе спинального шока. Сообщение I. Состояние гиперполяризации при спинальном шоке // Бюл. эксп. биол. и мед. 1959. № 2. С. 27–31.
5. Сорохтин Г.Н., Чумакова Т.А. К вопросу о природе спинального шока. Сообщение II. Влияние ионов калия и кальция на развитие спинального шока // Бюл. эксп. биол. и мед. 1959. № 5. С. 11–18.
6. Суфианова Г.З. Нейропротекторное действие агонистов аденозиновых рецепторов при фокальных ишемических и травматических повреждениях ЦНС: Дис.. д-ра мед. наук. Иркутск, 2003.
7. Шапкин А.Г. Диагностические возможности регистрации спонтанной биоэлектрической активности и механизмы изменения функционального состояния спинного мозга при повреждении (экспериментально-клиническое исследование): Дис.. канд. мед. наук. Новосибирск, 2005.
8. Штарк М.Б. Электрические потенциалы спинного мозга человека в норме и при патологии // Вопросы клиники, патофизиологии и терапии психических заболеваний. Пермь, 1959. С. 224–240.
9. Caspers H., Speckmann E.-J. Cortical DC shifts associated with changes of gas tensions in blood and tissue // In: A.Remond, ed., Handbook of Electroenceph. Clin. Neurophysiol. Vol. 10, Part. A. Amsterdam: Elsevier, 1974. P. 41–65.
10. Dzialek E. [Recordings of spinal cord bioelectric currents in man] // Neurol. Neurochir. Pol. 1975. Vol. 9. P. 453–459. Polish.
11. Eidelberg E., Sullivan J., Brigham A. Immediate consequences of spinal cord injury: possible role of potassium in axonal conduction block // Surg. Neurol. 1975. Vol. 3. P. 317–321.
12. Ertekin C., Sarica Y., Uckardesler L. Studies on the human spontaneous electromyelogram (EMyeloG). II. Patients with peripheral nerve, root and spinal cord disorders // Electroencephalogr. Clin. Neurophysiol. 1983. Vol. 55. P. 24–33.
13. Goodman R.M., Wachs K., Keller S., et al. Spontaneous spinal cord «injury potential» in the rat // Neurosurgery. 1985. Vol. 17. P. 757–759.
14. Hossmann K.A. Periinfarct depolarizations // Cerebrovasc. Brain Metab. Rev. 1996. Vol. 8. P. 195–208.
15. Maynard F.M.Jr., Bracken M.B., Creasey G., et al. International standards for neurological and functional classification of spinal cord injury. American Spinal Injury Association // Spinal Cord. 1997. Vol. 35. P. 266–274.
16. Niedermeyer E., Lopes da Silva F. (eds.) Electroencephalography, Basic Principles, Clinical Applications and Related Felds. Philadelphia, 2005.
17. Pool J.L. Electrospinogram (ESG). Spinal cord action potentials recorders from a paraplegic patients // J. Neurosurg. 1946. Vol. 3. P. 192–198.
18. Shimoji K., Kano T., Higashi H., et al. Evoked spinal electrograms recorded from epidural space in man // J Appl Physiol. 1972. Vol. 33. P. 468–471.
19. Sufianov A.A., Sufianova G.Z., Usov L.A., et al. Dynamic of the DC potential shifts at local compression injury of a spinal cord // Child`s Nervous System. 2004. Vol. 20. P. 292.
20. Visser P., Ten Cate J., Boeles J.T. [Electromyelography after transsection of the spinal cord in the cat, dog and rabbit] // J. Physiol. (Paris). 1958. Vol. 50. P. 557–560. French.
Review
For citations:
Sufianov A.A., Shapkin A.G., Sufianova G.Z., Shapkin Yu.G., Taborov M.V. POSSIBILITY OF SPONTANEOUS BIOELECTRIC ACTIVITY RECORDING IN THE SPINAL CORD INJURY. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2008;(4):058-064. (In Russ.) https://doi.org/10.14531/ss2008.4.58-64
Email this article 