INFORMATIVE VALUE OF PERCUTANEOUS TREPAN BIOPSY FOR DIFFERENTIAL DIAGNOSIS OF CIRCUMSCRIBED DESTRUCTIVE LESIONS OF THE SPINE
https://doi.org/10.14531/ss2012.1.62-66
Abstract
Objective. To assess informative value of diagnostic trepan biopsy for differential diagnosis of circumscribed destructive lesions of the spine in patients of different age groups.
Material and Methods. Percutaneous vertebral body trepan biopsy followed by cytological and histological investigations of bioptates was performed in 53 patients (20 adults and 33 children) having destructive lesions confined to a single spinal motion segment and admitted with a suspicion of tuberculous spondylitis. The structure of pathology and possible complications were determined.
Results. Diagnosis was substantiated by findings of cytological and histological investigation of bioptates in 75 % of patients.
Conclusion. Informative value of cytological and histological investigation of trepan biopsy sample may be higher if manipulation is performed earlier, before indication of antibacterial or tuberculostatic therapy. Trepan biopsy should be supplemented by aspiration biopsy with additional bacteriologic and cytological investigation if paravertebral soft-tissue component is available.
About the Authors
A. Y. Mushkin
Federal State Institution Saint-Petersburg Research Institute of Phthisiopulmonology
Russian Federation
Russian Federation
A. V. Alatortsev
Center for Specialized Medical Care to Patients with Extrapulmonary Tuberculosis, Balashiha
Russian Federation
Russian Federation
D. B. Malamashin
Federal State Institution Saint-Petersburg Research Institute of Phthisiopulmonology
Russian Federation
Russian Federation
E. O. Peretsmanas
Center for Specialized Medical Care to Patients with Extrapulmonary Tuberculosis, Balashiha
Russian Federation
Russian Federation
D. V. Kuklin
Federal State Institution Saint-Petersburg Research Institute of Phthisiopulmonology
Russian Federation
Russian Federation
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Review
For citations:
Mushkin A.Y., Alatortsev A.V., Malamashin D.B., Peretsmanas E.O., Kuklin D.V. INFORMATIVE VALUE OF PERCUTANEOUS TREPAN BIOPSY FOR DIFFERENTIAL DIAGNOSIS OF CIRCUMSCRIBED DESTRUCTIVE LESIONS OF THE SPINE. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2012;(1):62-66. (In Russ.) https://doi.org/10.14531/ss2012.1.62-66
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