Efficiency of using polyacrylic acid silver salt in decompression and stabilization surgery on the lumbar spine involving 1 to 3 segments
https://doi.org/10.14531/ss2019.2.73-80
Abstract
Objective. To determine possible effect of the preparation of an incomplete polyacrylic acid silver salt on the volume of intraoperative and postoperative blood loss in open posterior surgery on the spine involving up to three segments.
Material and Methods. Study design: randomized prospective multicenter cohort analysis. Level of evidence – IIb. The study was based on 90 patients aged 27 to 65 years who underwent decompression and stabilization surgical interventions on the lumbar spine through posterior median approach using transpedicular fixation system with fixation of up to three vertebrae. A comparison of perioperative blood loss volume in patients with local application of polyacrylic acid silver salt and without it was performed.
Results. The volume of inraoperative blood loss (the sample was described using the mean value and standard deviation M ± σ) in the study group was 258.1 ± 164.5 ml (min 90; max 890), in the control group – 405.5 ± 157.9 ml (min 190; max 950). The postoperative blood loss through drainage (M ± σ) was 81.500 ± 77.046 ml (min 20; max 400) in the study group, 151.560 ± 74.745 (min 20; max 600) in the control group. Comparison of both intraoperative and postoperative blood loss according to the Mann-Whitney U-test confirms the high statistical significance of differences (p < 0.01), which suggests the effectiveness of the preparation.
Conclusion. The use of incomplete polyacrylic acid silver salt in decompression and stabilization interventions on the lumbar spine involving 1 to 3 segments can effectively reduce the volume of blood loss both during surgery and in the postoperative period.
About the Authors
S. V. Kolesov
National Medical Research Centre for Traumatology and Orthopaedics n.a. N.N. Priorov
Russian Federation
Sergey Vasilyevich Kolesov, DMSc, Prof., Head of the Department of spinal pathology, Priorov str., 10, Moscow, 127299, Russia
Russian Federation
Sergey Vasilyevich Kolesov, DMSc, Prof., Head of the Department of spinal pathology, Priorov str., 10, Moscow, 127299, Russia
A. A. Grin
N.V. Sklifosovsky Scientific Research Institute of First Aid
Russian Federation
Andrey Anatolyevich Grin, DMSc, Chief external expert in neurosurgery of the Moscow Department of health, Bolshaya Sukharevskaya Sq., 3, Moscow, 129090, Russia
Russian Federation
Andrey Anatolyevich Grin, DMSc, Chief external expert in neurosurgery of the Moscow Department of health, Bolshaya Sukharevskaya Sq., 3, Moscow, 129090, Russia
L. Y. Slinyakov
I.M. Sechenov First Moscow State Medical University
Russian Federation
Leonid Yuryevich Slinyakov, DMSc, Professor of the Department of traumatology, Trubetskaya str., 8, buiol. 2, Moscow, 119991, Russia
Russian Federation
Leonid Yuryevich Slinyakov, DMSc, Professor of the Department of traumatology, Trubetskaya str., 8, buiol. 2, Moscow, 119991, Russia
N. S. Morozova
National Medical Research Centre for Traumatology and Orthopaedics n.a. N.N. Priorov
Russian Federation
Natalia Sergeyevna Morozova, MD, PhD, physician in the Department of spine pathology, Priorov str., 10, Moscow, 127299, Russia
Russian Federation
Natalia Sergeyevna Morozova, MD, PhD, physician in the Department of spine pathology, Priorov str., 10, Moscow, 127299, Russia
D. S. Gorbatyuk
National Medical Research Centre for Traumatology and Orthopaedics n.a. N.N. Priorov
Russian Federation
Dmitry Sergeyevich Gorbatyuk, junior researcher, Priorov str., 10, Moscow, 127299, Russia
Russian Federation
Dmitry Sergeyevich Gorbatyuk, junior researcher, Priorov str., 10, Moscow, 127299, Russia
O. E. Zheltyakov
National Medical Research Centre for Traumatology and Orthopaedics n.a. N.N. Priorov
Russian Federation
Oskar Evgenyevich Zheltyakov, resident in the Department of spinal pathology, Priorov
str., 10, Moscow, 127299, Russia
Russian Federation
Oskar Evgenyevich Zheltyakov, resident in the Department of spinal pathology, Priorov
str., 10, Moscow, 127299, Russia
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Review
For citations:
Kolesov S.V., Grin A.A., Slinyakov L.Y., Morozova N.S., Gorbatyuk D.S., Zheltyakov O.E. Efficiency of using polyacrylic acid silver salt in decompression and stabilization surgery on the lumbar spine involving 1 to 3 segments. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2019;16(2):73-80. https://doi.org/10.14531/ss2019.2.73-80
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