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Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika)

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Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort

https://doi.org/10.14531/ss2023.3.79-85

Abstract

Objective. To study the relationship between clinical and radiation variants of myelopathy and types of the neurogenic dysfunction of the lower urinary tract in patients with infectious spondylitis.

Material and Methods. A single-center cohort observational study was conducted with the analysis of medical records and a prospective examination of 20 patients with infectious spondylitis complicated by neurogenic dysfunction of the lower urinary tract.

Results. Infectious spondylitis can be complicated by the development of various urodynamic disorders, including neurogenic detrusor hyperactivity (30 %), its combination with detrusor-sphincter dissinergia (30 %) and a decrease in detrusor contractility (40 %). In 50 % of patients, an urodynamic examination revealed an increase in detrusor pressure of more than 40 cm water. There was no connection between the development of any type of lower urinary tract dysfunction and MRI types of myelopathy according to Vendatam, as well as between the level of spinal cord compression and the severity of neurological disorders according to AIS.

Conclusion. The results of the study do not confirm the existence of a relationship between the various characteristics of myelopathy in infectious spondylitis and the results of urodynamic examination. The limitation of the reliability of the results is the small number of observations. Studies with a larger sample are required to assess the relationship between the clinical and radiation characteristics of myelopathy and variants of neurogenic dysfunction of the lower urinary tract in patients with infectious spondylitis.

About the Authors

Aleksandr Igorevich Gorbunov
Saint-Petersburg State Research Institute of Phthisiopulmonology 2–4 Ligovskii ave., Saint-Petersburg, 191036, Russia
Russian Federation

MD, PhD, researcher of the Scientific-Research Laboratory of urogenital pathology



Mikhail Aleksandrovich Mushkin
Pavlov First Saint Petersburg State Medical University 6–8 L’va Tolstogo str., St. Petersburg, 194064, Russia
Russian Federation

MD, PhD, orthopedic traumatologist, teaching assistant, Department of traumatology and orthopedics



Diana Airatovna Kaumova
St. Petersburg State University 7–9 Universitetskaya emb., Saint-Petersburg, 199034, Russia
Russian Federation

student at Medical Faculty



Alexandr Nikolaevich Muraviev
Saint-Petersburg State Research Institute of Phthisiopulmonology; Private University «Saint-Petersburg Medico-Social Institute» 2–4 Ligovskii ave., Saint-Petersburg, 191036, Russia; 72 lit. A Kondratievsky ave., St. Petersburg, 195272, Russia
Russian Federation

MD, PhD, leading researcher, Head of the Scientific-Research Laboratory of cell biology and regenerative medicine, urologist;

Associate Professor of the Department of Surgical Diseases



Andrey Igorevich Gorelov
St. Petersburg State University 7–9 Universitetskaya emb., Saint-Petersburg, 199034, Russia
Russian Federation

DMSc, Prof., professor at the Department of Hospital Surgery



Nadezhda Valerievna Orlova
Saint-Petersburg State Research Institute of Phthisiopulmonology 2–4 Ligovskii ave., Saint-Petersburg, 191036, Russia
Russian Federation

MD, PhD, senior researcher of the Scientific-Research Laboratory of cell biology and regenerative medicine



Anna Andreevna Gorelova
Saint-Petersburg State Research Institute of Phthisiopulmonology; St. Petersburg State University 2–4 Ligovskii ave., Saint-Petersburg, 191036, Russia; 7–9 Universitetskaya emb., Saint-Petersburg, 199034, Russia
Russian Federation

MD, PhD, senior researcher, Head of the Scientific-Research Laboratory of urogenital pathology;

Associate Professor of the Department of Hospital Surgery



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Review

For citations:


Gorbunov A.I., Mushkin M.A., Kaumova D.A., Muraviev A.N., Gorelov A.I., Orlova N.V., Gorelova A.A. Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2023;20(3):79-85. https://doi.org/10.14531/ss2023.3.79-85



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ISSN 1810-8997 (Print)
ISSN 2313-1497 (Online)