Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort
https://doi.org/10.14531/ss2023.3.79-85
Abstract
Objective. To study the relationship between clinical and radiation variants of myelopathy and types of the neurogenic dysfunction of the lower urinary tract in patients with infectious spondylitis.
Material and Methods. A single-center cohort observational study was conducted with the analysis of medical records and a prospective examination of 20 patients with infectious spondylitis complicated by neurogenic dysfunction of the lower urinary tract.
Results. Infectious spondylitis can be complicated by the development of various urodynamic disorders, including neurogenic detrusor hyperactivity (30 %), its combination with detrusor-sphincter dissinergia (30 %) and a decrease in detrusor contractility (40 %). In 50 % of patients, an urodynamic examination revealed an increase in detrusor pressure of more than 40 cm water. There was no connection between the development of any type of lower urinary tract dysfunction and MRI types of myelopathy according to Vendatam, as well as between the level of spinal cord compression and the severity of neurological disorders according to AIS.
Conclusion. The results of the study do not confirm the existence of a relationship between the various characteristics of myelopathy in infectious spondylitis and the results of urodynamic examination. The limitation of the reliability of the results is the small number of observations. Studies with a larger sample are required to assess the relationship between the clinical and radiation characteristics of myelopathy and variants of neurogenic dysfunction of the lower urinary tract in patients with infectious spondylitis.
About the Authors
Aleksandr Igorevich GorbunovRussian Federation
MD, PhD, researcher of the Scientific-Research Laboratory of urogenital pathology
Mikhail Aleksandrovich Mushkin
Russian Federation
MD, PhD, orthopedic traumatologist, teaching assistant, Department of traumatology and orthopedics
Diana Airatovna Kaumova
Russian Federation
student at Medical Faculty
Alexandr Nikolaevich Muraviev
Russian Federation
MD, PhD, leading researcher, Head of the Scientific-Research Laboratory of cell biology and regenerative medicine, urologist;
Associate Professor of the Department of Surgical Diseases
Andrey Igorevich Gorelov
Russian Federation
DMSc, Prof., professor at the Department of Hospital Surgery
Nadezhda Valerievna Orlova
Russian Federation
MD, PhD, senior researcher of the Scientific-Research Laboratory of cell biology and regenerative medicine
Anna Andreevna Gorelova
Russian Federation
MD, PhD, senior researcher, Head of the Scientific-Research Laboratory of urogenital pathology;
Associate Professor of the Department of Hospital Surgery
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Review
For citations:
Gorbunov A.I., Mushkin M.A., Kaumova D.A., Muraviev A.N., Gorelov A.I., Orlova N.V., Gorelova A.A. Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2023;20(3):79-85. https://doi.org/10.14531/ss2023.3.79-85