SPINAL EPIDURAL ABSCESSES AS A COMPLICATION OF SPONDYLODISCITIS: A RETROSPECTIVE SINGLE-CENTER STUDY
https://doi.org/10.14531/ss2017.4.103-109
Abstract
Objective. To present the clinical course and outcomes of surgical treatment in patients with spinal epidural abscesses.
Material and Methods. Sixteen patients (7 males and 9 females) with clinical, neuroimaging and/or histological evidence of spinal epidural abscess were treated in 2015 and 2016 at our institution.
Results. The mean age of patients was 60.200 ± 10.387 years.
The period from disease onset to hospital admission ranged from 15 to 120 days. Upon hospitalization, only 3 patients (18.75 %) were neurologically intact. Seven patients (3.75 %) underwent interlaminotomy at one or more levels or hemilaminectomy. The remaining 9 patients (56.25 %) were treated with laminectomy, and 5 of them with additional posterior pedicle screw fixation. Disability decreased after surgery in 7 patients (43.75 %), and remained unchanged until hospital discharge in 7. Two patients (12.5 %) died.
Conclusion. Urgent surgery is the method of choice for patients with spinal epidural abscess. It allows decompression of neural structures, correction of spinal deformity by means of stabilization that aims at rapid mobilization of patients.
About the Authors
Borislav Dimitrov KitovBulgaria
Prof., MD, PhD, Head of Department of Neurosurgery
15A Vassil Aprilov Blvd, Medical University Plovdiv, 4002, Bulgaria
Hristo Bogdanov Jelyazkov
Bulgaria
Prof., MD, PhD, Head of Clinic of Neurosurgery, St George University Hospital, Plovdiv, Department of Neurosurgery, Medical University, Plovdiv
15A Vassil Aprilov Blvd, Medical University Plovdiv, 4002, Bulgaria
Aneta Simeonova Petkova
Bulgaria
MD, Assist. Prof., MD, Department of Neurosurgery
15A Vassil Aprilov Blvd, Medical University Plovdiv, 4002, Bulgaria
Ivo Kehayov
Bulgaria
Assist. Prof., MD, PhD, Department of Neurosurgery
15A Vassil Aprilov Blvd, Medical University Plovdiv, 4002, Bulgaria
Atanas Davarski
Bulgaria
Assist. Prof., MD, PhD, Department of Neurosurgery
15A Vassil Aprilov Blvd, Medical University Plovdiv, 4002, Bulgaria
Borislav Kalnev
Bulgaria
Assist. Prof., MD, Department of Neurosurgery15A Vassil Aprilov Blvd, Medical University Plovdiv, 4002, Bulgaria
Tanya Kitova
Bulgaria
Assoc. Prof., MD, PhD, Department of Anatomy, Histology and Embryology
15A Vassil Aprilov Blvd, Medical University Plovdiv, 4002, Bulgaria
References
1. Adogwa O, Karikari IO, Carr KR, Krucoff M, Ajay D, Fatemi P, Perez EL, Cheng JS, Bagley CA, Isaacs RE. Spontaneous spinal epidural abscess in patients 50 years of age and older: a 15-year institutional perspective and review of the literature: clinical article. J Neurosurg Spine. 2014; 20:344–349. DOI: 10.3171/2013.11.SPINE13527.
2. Arko L 4th, Quach E, Nguyen V, Chang D, Sukul V, Kim BS. Medical and surgical management of spinal epidural abscess:a systematic review. Neurosurg Focus. 2014;37:1–9. DOI: 10.3171/2014.6.FOCUS14127.
3. Butler JS, Shelly MJ, Timlin M, Powderly WG, O’Byrne JM. Nontuberculous pyogenic spinal infection in adults: a 12-year experience from a tertiary referral center. Spine. 2006;31:2695–2700. DOI: 10.1097/01.brs.0000244662.78725.37.
4. Chao D, Nanda A. Spinal epidural abscess: a diagnostic challenge. Am Fam Physician. 2002;65:1341–1346.
5. Chen SH, Chang WN, Lu CH, Chuang YC, Lui CC, Chen SF, Tsai NW, Chang CC, Chien CC, Huang CR. The clinical characteristics, therapeutic outcome, and prognostic factors of non-tuberculous bacterial spinal epidural abscess in adults: a hospital-based study. Acta Neurol Taiwan. 2011; 20:107–113.
6. Connor DE Jr, Chittiboina P, Caldito G, Nanda A. Comparison of operative and nonoperative management of spinal epidural abscess: a retrospective review of clinical and laboratory predictors of neurological outcome. J Neurosurg Spine. 2013;19:119–127. DOI: 10.3171/2013.3.SPINE12762.
7. Curry WT Jr, Hoh BL, Amin-Hanjani S, Eskandar EN. Spinal epidural abscess: clinical presentation, management, and outcome. Surg Neurol.2005;63:364–371. DOI: 10.1016/j.surneu.2004.08.081.
8. Darouiche RO. Spinal epidural abscess. N Engl J Med. 2006;355:2012–2020. DOI: 10.1056/NEJMra055111.
9. Eftimov T, Ninov K, Prandjev V, Hadzhiangelov I, Marinov N. [Results of surgicalt reatment in patients with primary non-specific spondylodicites]. Bulg Neurosurg. 2014;19(1–2): 21–28. In Bulgarian.
10. Hadjipavlou AG, Mader JT, Necessary JT, Muffoletto AJ. Hematogenous pyogenic spinal infections and their surgical management. Spine. 2000;25:1668–1679. DOI: 10.1097/00007632-200007010-00010.
11. Karikari IO, Powers CJ, Reynolds RM, Mehta AI, Isaacs RE. Management of a spontaneous spinal epidural abscess: a single-center 10-year experience. Neurosurgery. 2009;65:919–924. DOI: 10.1227/01.NEU.0000356972.97356.C5.
12. Khan SH, Hussain MS, Griebel RW, Hatting S. Comparison of primary and secondary spinal epidural abscesses: a retrospective analysis of 29 cases. Surg Neurol. 2003;59:28–33. DOI: 10.1016/S0090-3019(02)00925-4.
13. Kim SD, Melikian R, Ju KL, Zurakowski D, Wood KB, Bono CM, Harris MB. Independent predictors of failure of nonoperative management of spinal epidural abscesses. Spine J. 2014;14:1673–1679. DOI: 10.1016/j.spinee.2013.10.011.
14. Luzzati R, Giacomazzi D, Danzi MC, Tacconi L, Concia E, Vento S. Diagnosis, management and outcome of clinically suspected spinal infection. J Infect. 2009;58:259–265. DOI: 10.1016/j.jinf.2009.02.006.
15. Nakov V, Prandjev V, Stavrev E, Eftimov T. [Spontaneous spinal pyogenic epidural abscesses]. Bulg Neurosurg. 2015;2(1–2):32–41. In Bulgarian.
16. Oktenoglu Т, Sasani М, Cetin B, Bozkus H, Ercelen O, Vural M, Ozer AF, Sarioglu AC. Spontaneous pyogenic spinal epidural abscess. Turk Neurosurg. 2011;21:74–82.
17. Pradilla G, Ardila GP, Hsu W, Rigamonti D. Epidural abscesses of the CNS. Lancet Neurol.2009; 8:292–300. DOI: 10.1016/S1474-4422(09)70044-4.
18. Reihsaus E, Waldbaur H, Seeling W. Spinal epidural abscess: a meta-analysis of 915 patients. Neurosurg Rev. 2000;23:175–205.
19. Sendi P, Bregenzer T, Zimmerli W. Spinal epidural abscess in clinical practice. QJM 2008;101:1–12. DOI: 10.1093/qjmed/hcm100.
20. Schoenfeld AJ, Wahlquist TC. Mortality, complication risk, and total charges after the treatment of epidural abscess. Spine J. 2015; 15:249–255. DOI: 10.1016/j.spinee.2014.09.003.
21. Shweikeh F, Saeed K, Bukavina L, Zyck S, Drazin D, Steinmetz MP. An institutional series and contemporary review of bacterialspinal epidural abscess: current status and future directions. Neurosurg Focus.2014;37:E9. DOI: 10.3171/2014.6.FOCUS14146.
22. Zimmerer SM, Conen A, Muller AA, Sailer M, Taub E, Flückiger U, SchwenzerZimmerer KC. Spinal epidural abscess: aetiology, predisponent factors and clinical outcomes in a 4-year prospective study. Eur Spine J. 2011;20:2228–2234. DOI: 10.1007/s00586-011-1838-y
Review
For citations:
Kitov B.D., Jelyazkov H.B., Petkova A.S., Kehayov I., Davarski A., Kalnev B., Kitova T. SPINAL EPIDURAL ABSCESSES AS A COMPLICATION OF SPONDYLODISCITIS: A RETROSPECTIVE SINGLE-CENTER STUDY. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2017;14(4):103-109. https://doi.org/10.14531/ss2017.4.103-109