FEATURE ANALYSIS OF CENTRAL NERVOUS SYSTEM IN CHILDREN WITH IDIOPATHIC SCOLIOSIS USING 3DLOCEEG METHOD

Abstract

Objective. To analyze the application results of innovator program for the assessment of brain bioelectric activity 3DLocEEG. Material and Methods. The program was run to assess 131 electroencephalograms each recorded from 36 brain slices of 1-cm thickness (12 sagittal, 12 horizontal, and 12 coronal sclices) – a total of 4716 slices. The number of dipole sources in each slice was determined at the thresholds of 25, 50, and 75 % of maximum power. A total of 14148 slices were analyzed. The obtained data of three-dimensional distribution of equivalent dipoles were processed using a statistical software package «Statistica 6.0». Results. The analysis revealed abnormal unusual time-and-frequency pattern of the brain bioelectric activity. Discriminatory analysis of the obtained data showed that different variants of this pattern are reliably correlated with the most offensive characteristic of idiopathic scoliosis – its progressing or nonprgressing development. Detailed analysis allowed identification of brain parts most significant in generation of time-and-frequency pattern of bioelectric activity pathognomic for patients with idiopathic scoliosis. These are basal structures – hypothalamus, hypophysis, and pineal body. Abnormal bioelectric activity in these structures is considered as a sign of disregulation. Conclusion. The revealed signs of disregulation in the brain structures concern the processes controlling longitudinal growth of the spine and its components and can be one of the factors that induce idiopathic scoliosis.