ЭКСПЕРИМЕНТАЛЬНЫЕ МОДЕЛИ ДЕГЕНЕРАТИВНЫХ ЗАБОЛЕВАНИЙ МЕЖПОЗВОНКОВЫХ ДИСКОВ
Аннотация
Обзор литературы посвящен экспериментальным моделям дегенеративно-дистрофических заболеваний межпозвонковых дисков. Представлены основные подходы в биомоделировании патологии межпозвонковых дисков. Проведен анализ зарубежной литературы, в которой рассмотрены современные подходы и методики верификации патоморфологических процессов в тканях межпозвонковых дисков, выявлены недостатки различных методик и определены пути их преодоления.
Список литературы
1. Anderson D.G., Izzo M.W., Hall D.J., et al. Comparative gene expression profiling of normal and degenerative discs: analysis of a rabbit annular laceration model // Spine. 2002. Vol. 27. P. 1291–1296.
2. Ariga K., Miyamoto S., Nakase T., et al. The relationship between apoptosis of endplate chondrocytes and aging and degeneration of the intervertebral disc // Spine. 2001. Vol. 26. P. 2414–2420.
3. Bailey A.S., Adler F., Min Lai S., et al. A comparison between bipedal and quadrupedal rats: do bipedal rats actually assume an upright posture? // Spine. 2001. Vol. 26. P. E308–E313.
4. Bradford D.S., Cooper K.M., Oegema T.R.Jr. Chymopapain, chemonucleolysis and nucleus pulposus regeneration // J. Bone Joint Surg. Am. 1983. Vol. 65. P. 1220–1231.
5. Cassidy J.D., Yong-Hing K., Kirkaldy-Willis W.H., et al. A study of the effects of bipedism and upright posture on the lumbosacral spine and paravertebral muscles of the Wistar rat // Spine. 1988. Vol. 13. P. 301–308.
6. Ching C.T., Chow D.H., Yao F.Y., et al. Changes in nuclear composition following cyclic compression of the intervertebral disc in an in vivo rat-tail model // Med. Eng. Phys. 2004. Vol. 26. P. 587–594.
7. Ching C.T., Chow D.H., Yao F.Y., et al. The effect of cyclic compression on the mechanical properties of the inter-vertebral disc: an in vivo study in a rat tail model // Clin. Biomech. (Bristol, Avon). 2003. Vol. 18. P. 182–189.
8. Gruber H.E., Ashraf N., Kilburn J., et al. Vertebral endplate architecture and vascularization: application of micro-computerized tomography, a vascular tracer, and immunocytochemistry in analyses of disc degeneration in the aging sand rat // Spine. 2005. Vol. 30. P. 2593–2600.
9. Gruber H.E., Gordon B., Williams C., et al. Bone mineral density of lumbar vertebral end plates in the aging male sand rat spine // Spine. 2003. Vol. 28. P. 1766–1772.
10. Iatridis J.C., Mente P.L., Stokes I.A., et al. Compression-induced changes in intervertebral disc properties in a rat tail model // Spine. 1999. Vol. 24. P. 996–1002.
11. Kaapa E., Holm S., Han X., et al. Collagens in the injured porcine intervertebral disc // J. Orthop. Res. 1994. Vol. 12. P. 93–102.
12. Kim J.S., et al. Successful in vivo gene transfer to intervertebral discs in a slowly progressive and reproducible animal model of disc degeneration // 50th Annual Meeting of the Orthopaedic Research Society, San Francisco, 2004.
13. Kim K.S., Yoon S.T., Li J., et al. Disc degeneration in the rabbit: a biochemical and radiological comparison between four disc injury models // Spine. 2005. Vol. 30. P. 33–37.
14. Kroeber M.W., Unglaub F., Wang H., et al. New in vivo animal model to create intervertebral disc degeneration and to investigate the effects of therapeutic strategies to stimulate disc regeneration // Spine. 2002. Vol. 27. P. 2684–2690.
15. Lipson S.J., Muir H. Proteoglycans in experimental intervertebral disc degeneration // Spine. 1981. Vol. 6. P. 194–210.
16. Lotz J.C. Animal models of intervertebral disc degeneration: lessons learned // Spine. 2004. Vol. 29. P. 2742–2750.
17. Lotz J.C., Colliou O.K., Chin J.R., et al. Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and finite-element study // Spine. 1998. Vol. 23. P. 2493–2506.
18. MacLean J.J., Lee C.R., Grad S., et al. Effects of immobilization and dynamic compression on intervertebral disc cell gene expression in vivo // Spine. 2003. Vol. 28. P. 973–981.
19. Miyamoto S., Yonenobu K., Ono K. Experimental cervical spondylosis in the mouse // Spine. 1991. Vol. 16. P. S495–S500.
20. Moskowitz R.W., Ziv I., Denko C.W., et al. Spondylosis in sand rats: a model of intervertebral disc degeneration and hyperostosis // J. Orthop. Res. 1990. Vol. 8. P. 401–411.
21. Masuda K., Aota Y., Muehleman C., et al. A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration // Spine. 2005. Vol. 30. P. 5–14.
22. Norcross J.P., Lester G.E., Weinhold P., et al. An in vivo model of degenerative disc disease // J. Orthop. Res. 2003. Vol. 21. P. 183–188.
23. Pazzaglia U.E., Andrini L., Di Nucci A. The effects of mechanical forces on bones and joints. Experimental study on the rat tail // J. Bone Joint Surg. Br. 1997. Vol. 79. P. 1024–1030.
24. Phillips F.M., Reuben J., Wetzel F.T. Intervertebral disc degeneration adjacent to a lumbar fusion: an experimental rabbit model // J. Bone Joint Surg. Br. 2002. Vol. 84. P. 289–294.
25. Silberberg R. Histologic and morphometric observations on vertebral bone of aging sand rats // Spine. 1988. Vol. 13. P. 202–208.
26. Stokes I.A., Iatridis J.C. Mechanical conditions that accelerate intervertebral disc degeneration: overload versus immobilization // Spine. 2004. Vol. 29. P. 2724–2732.
27. Sugimura T., Kato F., Mimatsu K., et al. Experimental chemonucleolysis with chondroitinase ABC in monkeys // Spine. 1996. Vol. 21. P. 161–165.
28. Takahashi T., Kurihara H., Nakajima S., et al. Chemonucleolytic effects of chondroitinase ABC on normal rabbit intervertebral discs. Course of action up to 10 days postinjection and minimum effective dose // Spine. 1996. Vol. 21. P. 2405–2411.
29. Wilson C., Brown D., Najarian K., et al. Computer aided vertebral visualization and analysis: a methodology using the sand rat, a small animal model of disc degeneration // BMC Musculoskelet Disord. 2003. N 4. P. 4.
30. Yamada K., Tanabe S., Ueno H., et al. Investigation of the short-term effect of chemonucleolysis with chondroitinase ABC // J. Vet. Med. Sci. 2001. Vol. 63. P. 521–525.
31. Ziran B.H., Pineda S., Pokharna H., et all. Biomechanical, radiologic, and histopathologic correlations in the pathogenesis of experimental intervertebral disc disease // Spine. 1994. Vol. 19. P. 2159–2163.
32. Ziv I., Moskowitz R.W., Kraise I., et al. Physicochemical properties of the aging and diabetic sand rat intervertebral disc // J. Orthop. Res. 1992. Vol. 10. P. 205–210.
Для цитирования:
Волков А.В. ЭКСПЕРИМЕНТАЛЬНЫЕ МОДЕЛИ ДЕГЕНЕРАТИВНЫХ ЗАБОЛЕВАНИЙ МЕЖПОЗВОНКОВЫХ ДИСКОВ. "Хирургия позвоночника". 2007;(4):041-046. https://doi.org/10.14531/ss2007.4.41-46
For citation:
Volkov A.V. EXPERIMENTAL MODELS OF DEGENERATION DISC DISEASES. Hirurgiâ pozvonočnika (Spine Surgery). 2007;(4):041-046. (In Russ.) https://doi.org/10.14531/ss2007.4.41-46
Просмотров: 126
Послать статью по эл. почте 
