IN VIVO LONG-TERM FIXATION OF UNLOADED PEDICLE SCREWS: MECHANICAL AND HISTOLOGICAL STUDIES OF THE INTERFACE IN SHEEP
Abstract
Objectives. Pedicle screws were machined from five different materials used in orthopaedic surgery. The bone tissue reaction to these materials implanted as unloaded pedicle screws was investigated mechanically and histologically.
Methods. Ten pedicle screws of the same material were implanted per sheep in the lumbar region from L1 to L5. The bone tissue reaction to Ti alloy, c.p.Ti grade 1 and 4, 316L stainless steel and Vitallium fixation (unloaded pedicle screws) was evaluated mechanically and histologically.
Results. Ti alloy, c.p.Ti grade 4 and 316L stainless steel screws showed significant pull-out strength as compared to Vitallium and c.p. Ti grade 1 screws (p < 0.005). Histological analysis revealed direct bone contact to c.p. Ti and Ti alloy screws and the formation of new compact bone around the implant within the cancellous bone. The 316L stainless steel histological sections displayed few areas with direct bone contact, whereas Vitallium sections showed bone resorption all around the implants.
Conclusions. The five materials (screws) showed great pull-out forces but better osteointegration was observed with c.p.Ti and Ti alloy screws compared with Vitallium and 316L screws. Even if the 316L stainless steel material showed high pull-out strength, histologically its osteointegration was not as relevant as titanium material. Therefore, 316L stainless steel is more susceptible to the loosening than titanium.
About the Authors
Charles-Hilaire Rivard
Research Center, Sainte-Justine Hospital, Montreal, Canada; Ecole Polytechnique/Universite de Montreal, Institut de Genie Biomedical; 3Biorthex Inc., Montreal (QC), Canada
Russian Federation
Russian Federation
Souad Rhalmi
Research Center, Sainte-Justine Hospital, Montreal, Canada
Russian Federation
Russian Federation
Christine Coillard
Research Center, Sainte-Justine Hospital, Montreal, Canada
Russian Federation
Russian Federation
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Review
For citations:
Rivard Ch., Rhalmi S., Coillard Ch. IN VIVO LONG-TERM FIXATION OF UNLOADED PEDICLE SCREWS: MECHANICAL AND HISTOLOGICAL STUDIES OF THE INTERFACE IN SHEEP. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2004;(4):107-114. (In Russ.)
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