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Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika)

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Biomechanical aspects of spinal sagittal balance in achondroplasia patients during Ilizarov limb lengthening

https://doi.org/10.14531/2018.4.7-14

Abstract

Objective. To review specific features of spinal sagittal balance in achondroplasia patients at stages of lower limb lengthening using the Ilizarov method.

Material and Methods. Cross-sectional clinical and radiological study was performed in 29 achondroplasia patients prior to lower limb lengthening and at lengthening stages using the Ilizarov method. Parameters of sagittal balance of the spine and pelvis were evaluated radiologically. Clinical evaluation included examination, and assessment of neurological status and pain level.

Results. Clinical manifestations of sagittal imbalance included hypokyphosis of the thoracic spine in 44.8 % of cases and increased lumbar lordosis in 55.2 %. No neurological disorders were diagnosed in patients. Pain scores 2 to 4 were observed in 17.2 % ofcases. After staged lower limb lengthening by 19.8 ± 3.3 cm, it was revealed that the values of the thoracic kyphosis, lumbar lordosis and the angle of the sacrum tilt improved and approached those of healthy peers. Vertical sagittal alignment measurements correlated with those of thoracic kyphosis. Thoracic kyphosis showed a correlation with lumbar lordosis. Pelvic indices had a moderate correlation with lumbar lordosis.

Conclusion. Biomechanically substantiated transosseous compression-distraction osteosynthesis by Ilizarov technique used for lower limb lengthening in achondroplasia patients improves spinal sagittal balance parameters.

About the Authors

O. G. Prudnikova
Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics
Russian Federation

DMSc, senior researcher at scientific-clinical laboratory of axial skeleton pathology and neurosurgery, head of traumatologicorthopedic department No. 10

M. Ulyanovoy str., 6, 640014, Kurgan



A. M. Aranovich
Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics
Russian Federation

DMSc, Prof., chief researcher of the scientific and clinical laboratory for deformity correction and limb lengthening, head of traumatologic-orthopedic department. No 17

M. Ulyanovoy str., 6, 640014, Kurgan



Yu. A. Mushtaeva
Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics
Russian Federation

PhD in technical sciences, specialist of information and analytical department

M. Ulyanovoy str., 6, 640014, Kurgan



A. V. Gubin
Russian Ilizarov Scientific Center for Restorative Traumatology and Orthopaedics
Russian Federation

DMSc, Director

M. Ulyanovoy str., 6, 640014, Kurgan



References

1. Karikari IO, Mehta AI, Solakoglu C, Bagley CA, Ain MC, Gottfried ON. Sagittal spinopelvic parameters in children with achondroplasia: identification of 2 distinct groups. J Neurosurg Spine. 2012;17:57–60. DOI: 10.3171/2012.3.SPINE11735.

2. Lonstein JE. Treatment of kyphosis and lumbar stenosis in achondroplasia. In: Nicoletti B, Kopits SE, Ascani E, McKusick VA, Dryburgh SC (eds). Human Achondroplasia. Basic Life Sciences. Springer, Boston, MA, 1988;48:283–292. DOI: 10.1007/978-1-4684-8712-1_38.

3. Колесов С.В., Снетков А.А., Сажнев М.Л. Хирургическое лечение деформации позвоночника при ахондроплазии // Хирургия позвоночника. 2013. № 4. С. 17–22. [Kolesov SV, Snetkov AA, Sazhnev ML. Surgical treatment for spine deformity in achondroplasia. Hir. Pozvonoc. 2013;(4):017–022. In Russian]. DOI:10.14531/ss2013.4.17-22.

4. Carter EM, Davis JG, Raggio CL. Advances in understanding etiology of achondroplasia and review of management. Curr Opin Pediatr. 2007;19:32–37. DOI: 10.1097/MOP.0b013e328013e3d9.

5. Hong JY, Suh SW, Modi HN, Park JW, Park JH. Analysis of sagittal spinopelvic parameters in achondroplasia. Spine. 2011;36:E1233–E1239. DOI: 10.1097/BRS.0b013e3182063e89.

6. Misra SN, Morgan HW. Thoracolumbar spinal deformity in achondroplasia. Neurosurg Focus. 2003;14:e4. DOI: 10.3171/foc.2003.14.1.5.

7. Sciubba DM, Noggle JC, Marupudi NI, Bagley CA, Bookland M, Carson BS Sr, Ain MC, Jallo GI. Spinal stenosis surgery in pediatric patients with achondroplasia. J Neurosurg. 2007;106(5 Suppl):372–378. DOI: 10.3171/ped.2007.106.5.372.

8. Thomeer RT, van Dijk JM. Surgical treatment of lumbar stenosis in achondroplasia. J Neurosurg. 2002;96(3 Suppl):292–297.

9. Kahanovitz N, Rimoin DL, Sillence DO. The clinical spectrum of lumbar spine disease in achondroplasia. Spine. 1982;7:137–140. DOI: 10.1097/00007632-198203000-00008.

10. Rimoin DL. Clinical variability in achondroplasia. Human achondroplasia. A multidisciplinary approach. In: Nicoletti B, Kopits SE, Ascani E, McKusick VA, Dryburgh SC (eds). Human Achondroplasia. Basic Life Sciences. Springer, Boston, MA, 1988;48:123–127. DOI: 10.1007/978-1-4684-8712-1_16.

11. Srikumaran U, Woodard EJ, Leet AI, Rigamonti D, Sponseller PD, Ain MC. Pedicle and spinal canal parameters of the lower thoracic and lumbar vertebrae in the achondroplast population. Spine. 2007;32:2423–2431. DOI: 10.1097/BRS.0b013e3181574286.

12. During J, Goudfrooij H, Keessen W, Beeker TW, Crowe A. Toward standards for posture. Postural characteristics of the lower back system in normal and pathologic conditions. Spine. 1985;10:83–87. DOI: 10.1097/00007632-198501000-00013.

13. Stagnara P, De Mauroy JC, Dran G, Gonon G, Costanzo G, Dimnet J, Pasquet A. Reciprocal angulation of vertebral bodies in a sagittal plane: approach to references for the evaluation of kyphosis and lordosis. Spine. 1982;7:335–342. DOI: 10.1097/00007632-198207000-00003.

14. Borkhuu D, Nagaraju DK, Chan G, Holmes L, Mackenzie WG. Factors related to progression of thoracolumbar kyphosis in children with achondroplasia: a retrospective cohort study of forty-eight children treated in a comprehensive orthopaedic center. Spine. 2009;34:1699–1705. DOI: 10.1097/BRS.0b013e3181ac8f9d.

15. Qi X, Matsumoto M, Ishii K, Nakamura M, Chiba K, Toyama Y. Posterior osteotomy and instrumentation for thoracolumbar kyphosis in patients with achondroplasia. Spine. 2006;31:E606–E610. DOI: 10.1097/01.brs.0000229262.87720.9b.

16. Kopits SE. Thoracolumbar kyphosis and lumbosacral hyperlordosis in achondroplastic children. In: Nicoletti B, Kopits SE, Ascani E, McKusick VA, Dryburgh SC (eds). Human Achondroplasia. Basic Life Sciences. Springer, Boston, MA, 1988;48:241–255. DOI: 0.1007/978-1-4684-8712-1_34.

17. Дьячкова Г.В., Аранович А.М., Новикова О.С., Щукин А.А. Клиникорентгенологические особенности пояснично-крестцового отдела позвоночника у больных ахондроплазией // Гений ортопедии. 2000. № 4. С. 46–48. [Diachkova GV, Aranovich AM, Novikova OS, Shchukin AA. Clinical-and-roentgenological distinctions of the lumbosacral spine in patients with achondroplasia. Genii Ortopedii. 2000;(4):46–48. In Russian].

18. Mac-Thiong JM, Berthonnaud E, Dimar JR 2nd, Betz RR, Labelle H. Sagittal alignment of the spine and pelvis during growth. Spine. 2004;29:1642–1647.

19. Marty C, Boisaubert B, Descamps H, Montigny JP, Hecquet J, Legaye J, DuvalBeaupere J. The sagittal anatomy of the sacrum among young adults, infants, and spondylolisthesis patients. Eur Spine J. 2002;11:119–125. DOI: 10.1007/s00586-001-0349-7.

20. Шевцов В.И., Дьячкова Г.В., Новикова О.С. Возрастные рентгенологические особенности позвоночника у больных ахондроплазией // Вестник рентгенологии и радиологии. 1999. № 6. С. 32–34. [Shevtsov VI, Dyachkova GV, Novikova OS. Agerelated X-ray features of the spine in patients with achondroplasia. Vestnik Rentgenologii i Radiologii.1999;(6):32-34. In Russian].

21. Duval-Beaupere G, Schmidt C, Cosson P. A Barycentremetric study of the sagittal shape of spine and pelvis: the conditions required for an economic standing position. Ann Biomed Eng. 1992;20:451–462. DOI: 10.1007/BF02368136.

22. Ленке Л., Боши-Аджей О., Ванг Я. Остеотомия позвоночника. М.; СПб., 2016. [Lenke L, Boachie-Adjei O, Wang Y. Spinal Osteotomy. Transl. from English. Moscow, St. Petersburg, 2016. In Russian].

23. Le Huec JC, Aunoble S, Philippe L, Nicolas P. Pelvic parameters: origin and significance. Eur Spine J. 2011;20Suppl 5:S564–S571. DOI: 10.1007/s00586-011-1940-1.

24. Lafage V, Schwab F, Patel A, Nawkinson N, Farcy JP. Pelvic tilt and truncal inclination: two key radiographic parameters in the setting of adults with spinal deformity. Spine. 2009;34:E599–E606. DOI: 10.1097/BRS.0b013e3181aad219.

25. Аранович А.М., Климов О.В., Неретин А.С. Эргономические аспекты планирования реконструкции опорно-двигательного аппарата пациентов с ахондроплазией // Гений ортопедии. 2014. № 4. С. 72–75. [Aranovich АМ, Klimov OV, Neretin AS. Ergonomic aspects of planning the locomotor system reconstruction of patients with achondroplasia. Genii Ortopedii. 2014;(4):72–75. In Russian].

26. Новиков К.И., Аранович А.М., Зыков А.Г., Щукин А.А., Климов О.В. Способ увеличения роста у больных с ахондроплазией. Патент 2281047 РФ. Заявка № 2003132217/14 от 03.11.2003. Опубл. 10.08.2006; Бюл. № 22. [Novikov KI, Aranovich AM, Zykov AG, Shchukin AA, Klimov OV. Method for increasing the height in patients with achondroplasia.Patent RU 2281047. Appl. 03.11.2003; publ. 10.08.2006.Bul. 22].


Review

For citations:


Prudnikova O.G., Aranovich A.M., Mushtaeva Yu.A., Gubin A.V. Biomechanical aspects of spinal sagittal balance in achondroplasia patients during Ilizarov limb lengthening. Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2018;15(4):7-14. https://doi.org/10.14531/2018.4.7-14



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