ЧТО ЖЕ ТАКОЕ ИДИОПАТИЧЕСКИЙ СКОЛИОЗ?
https://doi.org/10.14531/ss2016.4.104-110
Аннотация
В лекции на основе многолетнего опыта исследований рассмотрены спорные вопросы о деформации позвоночника и сделаны некоторые обобщения. Дано определение сколиотической болезни. Это нарушение морфогенеза позвоночника в раннем эмбриогенезе, реализуемое на стадии роста в деформацию позвоночника с клиническими вариантами течения, зависящими
от степени нарушения морфогенеза. Эктопическая локализация в пластинке роста тел позвонков клеток, производных нервного гребня, генетически не детерминированных к хондрогенезу и процессу роста – этиологический фактор сколиотической болезни. Локальное нарушение хондрогенеза в пластинке роста тел позвонков – причина асимметрии роста и формирования
деформации позвоночника. Вариабельность структурных изменений и прогноз прогрессирования зависят от степени нарушения морфогенетических процессов, заложенных в эмбриогенезе. Фенотип сколиотического позвоночника – первичная сколиотическая, кифотическая деформация позвоночника с вариантами течения, зависящими от стадии болезни.
Перспектива исследований: создание экспериментальной модели сколиотической болезни с клиническими вариантами течения и разработка превентивной коррекции исследуемой патологии.
Об авторе
Алла Михайловна Зайдман
Новосибирский НИИ травматологии и ортопедии им. Я.Л. Цивьяна
Россия
Россия
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Рецензия
Для цитирования:
Зайдман А.М. ЧТО ЖЕ ТАКОЕ ИДИОПАТИЧЕСКИЙ СКОЛИОЗ? Хирургия позвоночника. 2016;13(4):104-110. https://doi.org/10.14531/ss2016.4.104-110
For citation:
Zaidman A.M. WHAT IS IDIOPATHIC SCOLIOSIS? Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika). 2016;13(4):104-110. https://doi.org/10.14531/ss2016.4.104-110
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