ЧТО ЖЕ ТАКОЕ ИДИОПАТИЧЕСКИЙ СКОЛИОЗ?


https://doi.org/10.14531/ss2016.4.104-110

Полный текст:


Аннотация

В лекции на основе многолетнего опыта исследований рассмотрены спорные вопросы о деформации позвоночника и сделаны некоторые обобщения. Дано определение сколиотической болезни. Это нарушение морфогенеза позвоночника в раннем эмбриогенезе, реализуемое на стадии роста в деформацию позвоночника с клиническими вариантами течения, зависящими от степени нарушения морфогенеза. Эктопическая локализация в пластинке роста тел позвонков клеток, производных нервного гребня, генетически не детерминированных к хондрогенезу и процессу роста - этиологический фактор сколиотической болезни. Локальное нарушение хондрогенеза в пластинке роста тел позвонков - причина асимметрии роста и формирования деформации позвоночника. Вариабельность структурных изменений и прогноз прогрессирования зависят от степени нарушения морфогенетических процессов, заложенных в эмбриогенезе. Фенотип сколиотического позвоночника - первичная сколиотическая, кифотическая деформация позвоночника с вариантами течения, зависящими от стадии болезни. Перспектива исследований: создание экспериментальной модели сколиотической болезни с клиническими вариантами течения и разработка превентивной коррекции исследуемой патологии.

Об авторе

Алла Михайловна Зайдман
Новосибирский НИИ травматологии и ортопедии им. Я.Л. Цивьяна
Россия


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Для цитирования: Зайдман А.М. ЧТО ЖЕ ТАКОЕ ИДИОПАТИЧЕСКИЙ СКОЛИОЗ? "Хирургия позвоночника". 2016;13(4):104-110. https://doi.org/10.14531/ss2016.4.104-110

For citation: Zaidman A.M. WHAT IS IDIOPATHIC SCOLIOSIS? Hirurgiâ pozvonočnika (Spine Surgery). 2016;13(4):104-110. (In Russ.) https://doi.org/10.14531/ss2016.4.104-110

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